Physical Properties | | | |
Molecular Weight: 495.373 g/mol | logS: -7.79588 | SlogP: 5.52942 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.030034 | Sterimol/B1: 3.68814 | Sterimol/B2: 3.77936 | Sterimol/B3: 6.61308 |
Sterimol/B4: 9.34512 | Sterimol/L: 20.4316 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 769.948 | Positive charged surface: 430.765 | Negative charged surface: 339.183 | Volume: 435.125 |
Hydrophobic surface: 673.131 | Hydrophilic surface: 96.817 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |