Physical Properties | | | |
Molecular Weight: 477.511 g/mol | logS: -7.53209 | SlogP: 5.5319 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0293998 | Sterimol/B1: 2.44576 | Sterimol/B2: 2.6129 | Sterimol/B3: 4.0202 |
Sterimol/B4: 14.4755 | Sterimol/L: 19.7053 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 777.002 | Positive charged surface: 462.437 | Negative charged surface: 314.565 | Volume: 437 |
Hydrophobic surface: 683.506 | Hydrophilic surface: 93.496 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |