Physical Properties | | | |
Molecular Weight: 392.499 g/mol | logS: -4.473 | SlogP: 4.02264 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0577075 | Sterimol/B1: 2.47616 | Sterimol/B2: 3.32814 | Sterimol/B3: 3.35406 |
Sterimol/B4: 12.6121 | Sterimol/L: 15.8929 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 661.634 | Positive charged surface: 529.573 | Negative charged surface: 126.497 | Volume: 390.125 |
Hydrophobic surface: 629.531 | Hydrophilic surface: 32.103 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |