Physical Properties | | | |
Molecular Weight: 403.478 g/mol | logS: -5.25832 | SlogP: 4.4716 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0949648 | Sterimol/B1: 2.66666 | Sterimol/B2: 2.91401 | Sterimol/B3: 5.56784 |
Sterimol/B4: 8.22271 | Sterimol/L: 18.3651 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 736.584 | Positive charged surface: 473.07 | Negative charged surface: 263.514 | Volume: 398.375 |
Hydrophobic surface: 637.393 | Hydrophilic surface: 99.191 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |