Physical Properties | | | |
Molecular Weight: 406.529 g/mol | logS: -6.40824 | SlogP: 7.33237 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.245346 | Sterimol/B1: 3.01932 | Sterimol/B2: 4.51774 | Sterimol/B3: 6.17926 |
Sterimol/B4: 11.7793 | Sterimol/L: 15.5724 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 721.483 | Positive charged surface: 456.197 | Negative charged surface: 254.54 | Volume: 414.25 |
Hydrophobic surface: 680.552 | Hydrophilic surface: 40.931 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 1 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |