Physical Properties | | | |
Molecular Weight: 418.469 g/mol | logS: -6.29099 | SlogP: 3.70687 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0686179 | Sterimol/B1: 3.0265 | Sterimol/B2: 3.78248 | Sterimol/B3: 5.45976 |
Sterimol/B4: 8.61634 | Sterimol/L: 17.9135 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 715.914 | Positive charged surface: 438.435 | Negative charged surface: 277.479 | Volume: 407 |
Hydrophobic surface: 604.359 | Hydrophilic surface: 111.555 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |