Physical Properties | | | |
Molecular Weight: 420.961 g/mol | logS: -6.60112 | SlogP: 4.4293 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.110138 | Sterimol/B1: 3.61457 | Sterimol/B2: 4.65677 | Sterimol/B3: 6.99034 |
Sterimol/B4: 7.18729 | Sterimol/L: 15.1352 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 655.843 | Positive charged surface: 367.43 | Negative charged surface: 288.413 | Volume: 387.125 |
Hydrophobic surface: 533.957 | Hydrophilic surface: 121.886 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |