Physical Properties | | | |
Molecular Weight: 416.525 g/mol | logS: -4.2473 | SlogP: 4.01247 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0615913 | Sterimol/B1: 2.39178 | Sterimol/B2: 5.03613 | Sterimol/B3: 5.46248 |
Sterimol/B4: 8.88025 | Sterimol/L: 19.2991 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 712.317 | Positive charged surface: 485.749 | Negative charged surface: 226.568 | Volume: 418.75 |
Hydrophobic surface: 627.893 | Hydrophilic surface: 84.424 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |