Physical Properties | | | |
Molecular Weight: 396.34 g/mol | logS: -4.46167 | SlogP: 4.0639 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.161315 | Sterimol/B1: 3.28734 | Sterimol/B2: 3.76824 | Sterimol/B3: 3.88979 |
Sterimol/B4: 7.41046 | Sterimol/L: 12.9937 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 532.13 | Positive charged surface: 262.148 | Negative charged surface: 269.983 | Volume: 320.375 |
Hydrophobic surface: 305.889 | Hydrophilic surface: 226.241 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |