Physical Properties | | | |
Molecular Weight: 414.195 g/mol | logS: -4.9957 | SlogP: 3.1406 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0620135 | Sterimol/B1: 3.07725 | Sterimol/B2: 3.08903 | Sterimol/B3: 3.53463 |
Sterimol/B4: 7.22497 | Sterimol/L: 15.439 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 535.369 | Positive charged surface: 273.268 | Negative charged surface: 262.101 | Volume: 292.875 |
Hydrophobic surface: 418.002 | Hydrophilic surface: 117.367 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |