Physical Properties | | | |
Molecular Weight: 524.686 g/mol | logS: -7.4419 | SlogP: 5.3276 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0361761 | Sterimol/B1: 2.52895 | Sterimol/B2: 3.93716 | Sterimol/B3: 5.11289 |
Sterimol/B4: 8.64835 | Sterimol/L: 24.4391 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 830.825 | Positive charged surface: 403.034 | Negative charged surface: 427.791 | Volume: 465.5 |
Hydrophobic surface: 627.014 | Hydrophilic surface: 203.811 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |