Physical Properties | | | |
Molecular Weight: 456.994 g/mol | logS: -7.30142 | SlogP: 5.2415 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0741259 | Sterimol/B1: 3.86358 | Sterimol/B2: 4.01029 | Sterimol/B3: 4.02427 |
Sterimol/B4: 10.6773 | Sterimol/L: 19.0935 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 753.983 | Positive charged surface: 404.788 | Negative charged surface: 349.195 | Volume: 424.625 |
Hydrophobic surface: 626.003 | Hydrophilic surface: 127.98 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |