Physical Properties | | | |
Molecular Weight: 401.26 g/mol | logS: -5.38284 | SlogP: 3.95608 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0418591 | Sterimol/B1: 2.54686 | Sterimol/B2: 2.92409 | Sterimol/B3: 4.49458 |
Sterimol/B4: 8.93609 | Sterimol/L: 18.7303 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 631.176 | Positive charged surface: 366.956 | Negative charged surface: 264.221 | Volume: 343.25 |
Hydrophobic surface: 520.199 | Hydrophilic surface: 110.977 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |