Physical Properties | | | |
Molecular Weight: 376.477 g/mol | logS: -4.47359 | SlogP: 3.04302 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0436173 | Sterimol/B1: 2.50913 | Sterimol/B2: 2.53373 | Sterimol/B3: 5.41836 |
Sterimol/B4: 6.89763 | Sterimol/L: 21.4226 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 658.179 | Positive charged surface: 403.081 | Negative charged surface: 255.098 | Volume: 358.125 |
Hydrophobic surface: 517.848 | Hydrophilic surface: 140.331 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |