Physical Properties | | | |
Molecular Weight: 404.473 g/mol | logS: -6.43654 | SlogP: 5.6653 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0273685 | Sterimol/B1: 2.54544 | Sterimol/B2: 3.72159 | Sterimol/B3: 3.84181 |
Sterimol/B4: 11.6441 | Sterimol/L: 16.8173 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 708.547 | Positive charged surface: 400.434 | Negative charged surface: 297.041 | Volume: 395.875 |
Hydrophobic surface: 623.166 | Hydrophilic surface: 85.381 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |