Physical Properties | | | |
Molecular Weight: 408.429 g/mol | logS: -7.18843 | SlogP: 3.8517 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0463162 | Sterimol/B1: 2.48445 | Sterimol/B2: 3.18958 | Sterimol/B3: 3.799 |
Sterimol/B4: 9.77512 | Sterimol/L: 17.2108 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 647.308 | Positive charged surface: 302.69 | Negative charged surface: 344.618 | Volume: 359 |
Hydrophobic surface: 495.79 | Hydrophilic surface: 151.518 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 1 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |