Physical Properties | | | |
Molecular Weight: 438.951 g/mol | logS: -5.73932 | SlogP: 4.3853 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.13679 | Sterimol/B1: 3.32535 | Sterimol/B2: 4.26482 | Sterimol/B3: 5.68799 |
Sterimol/B4: 8.4221 | Sterimol/L: 16.512 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 672.927 | Positive charged surface: 367.156 | Negative charged surface: 305.771 | Volume: 390.5 |
Hydrophobic surface: 590.663 | Hydrophilic surface: 82.264 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |