Physical Properties | | | |
Molecular Weight: 354.366 g/mol | logS: -4.83786 | SlogP: 3.80032 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0459339 | Sterimol/B1: 2.09929 | Sterimol/B2: 3.23475 | Sterimol/B3: 4.05444 |
Sterimol/B4: 11.3895 | Sterimol/L: 16.6623 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 624.327 | Positive charged surface: 417.696 | Negative charged surface: 206.631 | Volume: 322.25 |
Hydrophobic surface: 449.782 | Hydrophilic surface: 174.545 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |