Physical Properties | | | |
Molecular Weight: 274.272 g/mol | logS: -2.141 | SlogP: 2.67077 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0675911 | Sterimol/B1: 2.42608 | Sterimol/B2: 3.62377 | Sterimol/B3: 4.28181 |
Sterimol/B4: 4.82922 | Sterimol/L: 14.6772 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 487.095 | Positive charged surface: 315.478 | Negative charged surface: 171.618 | Volume: 244.875 |
Hydrophobic surface: 290.179 | Hydrophilic surface: 196.916 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |