Physical Properties | | | |
Molecular Weight: 479.564 g/mol | logS: -4.9891 | SlogP: 5.1527 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.170465 | Sterimol/B1: 3.52613 | Sterimol/B2: 3.75468 | Sterimol/B3: 6.81369 |
Sterimol/B4: 10.0334 | Sterimol/L: 18.273 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 730.749 | Positive charged surface: 433.763 | Negative charged surface: 292.899 | Volume: 439.375 |
Hydrophobic surface: 638.14 | Hydrophilic surface: 92.609 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |