Physical Properties | | | |
Molecular Weight: 472.427 g/mol | logS: -6.51892 | SlogP: 5.3235 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.051222 | Sterimol/B1: 2.48197 | Sterimol/B2: 3.55667 | Sterimol/B3: 3.75958 |
Sterimol/B4: 11.5032 | Sterimol/L: 20.5332 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 754.24 | Positive charged surface: 461.807 | Negative charged surface: 292.433 | Volume: 434.875 |
Hydrophobic surface: 625.131 | Hydrophilic surface: 129.109 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |