Physical Properties | | | |
Molecular Weight: 495.003 g/mol | logS: -7.21672 | SlogP: 4.842 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.066738 | Sterimol/B1: 2.42362 | Sterimol/B2: 5.63919 | Sterimol/B3: 6.36402 |
Sterimol/B4: 10.3303 | Sterimol/L: 19.4152 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 777.898 | Positive charged surface: 367.904 | Negative charged surface: 409.994 | Volume: 446 |
Hydrophobic surface: 668.211 | Hydrophilic surface: 109.687 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |