Physical Properties | | | |
Molecular Weight: 424.315 g/mol | logS: -5.76962 | SlogP: 4.19344 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0263249 | Sterimol/B1: 2.10806 | Sterimol/B2: 2.52491 | Sterimol/B3: 4.69272 |
Sterimol/B4: 9.7437 | Sterimol/L: 17.937 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 672.091 | Positive charged surface: 375.949 | Negative charged surface: 296.142 | Volume: 348.875 |
Hydrophobic surface: 569.854 | Hydrophilic surface: 102.237 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |