Physical Properties | | | |
Molecular Weight: 462.888 g/mol | logS: -7.28991 | SlogP: 4.9181 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0685422 | Sterimol/B1: 2.41415 | Sterimol/B2: 3.6385 | Sterimol/B3: 3.96384 |
Sterimol/B4: 11.9633 | Sterimol/L: 17.8476 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 729.169 | Positive charged surface: 428.605 | Negative charged surface: 300.564 | Volume: 399.125 |
Hydrophobic surface: 481.651 | Hydrophilic surface: 247.518 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |