Physical Properties | | | |
Molecular Weight: 401.132 g/mol | logS: -5.826 | SlogP: 4.5623 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.07792 | Sterimol/B1: 2.66661 | Sterimol/B2: 3.19781 | Sterimol/B3: 4.23212 |
Sterimol/B4: 6.23836 | Sterimol/L: 16.0373 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 532.576 | Positive charged surface: 140.802 | Negative charged surface: 391.774 | Volume: 277.375 |
Hydrophobic surface: 452.72 | Hydrophilic surface: 79.856 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |