Physical Properties | | | |
Molecular Weight: 399.45 g/mol | logS: -6.00472 | SlogP: 4.8088 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0382908 | Sterimol/B1: 2.54104 | Sterimol/B2: 3.83243 | Sterimol/B3: 4.05196 |
Sterimol/B4: 7.32717 | Sterimol/L: 18.9329 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 677.662 | Positive charged surface: 453.747 | Negative charged surface: 223.915 | Volume: 385.125 |
Hydrophobic surface: 617.829 | Hydrophilic surface: 59.833 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |