Physical Properties | | | |
Molecular Weight: 419.549 g/mol | logS: -6.70927 | SlogP: 5.536 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.159548 | Sterimol/B1: 2.40469 | Sterimol/B2: 3.40155 | Sterimol/B3: 6.34733 |
Sterimol/B4: 8.22643 | Sterimol/L: 16.7189 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 702.059 | Positive charged surface: 400.813 | Negative charged surface: 301.246 | Volume: 403.125 |
Hydrophobic surface: 549.769 | Hydrophilic surface: 152.29 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |