Physical Properties | | | |
Molecular Weight: 378.468 g/mol | logS: -4.99657 | SlogP: 4.92717 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.145556 | Sterimol/B1: 2.14452 | Sterimol/B2: 2.54249 | Sterimol/B3: 5.29433 |
Sterimol/B4: 11.5736 | Sterimol/L: 15.8099 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 669.992 | Positive charged surface: 444.396 | Negative charged surface: 225.596 | Volume: 384.5 |
Hydrophobic surface: 620.333 | Hydrophilic surface: 49.659 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |