Physical Properties | | | |
Molecular Weight: 415.489 g/mol | logS: -6.00154 | SlogP: 5.00117 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0385858 | Sterimol/B1: 3.3767 | Sterimol/B2: 3.53418 | Sterimol/B3: 3.61198 |
Sterimol/B4: 9.72328 | Sterimol/L: 19.0577 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 736.545 | Positive charged surface: 418.431 | Negative charged surface: 308.222 | Volume: 410.75 |
Hydrophobic surface: 604.212 | Hydrophilic surface: 132.333 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |