Physical Properties | | | |
Molecular Weight: 385.464 g/mol | logS: -4.08258 | SlogP: 3.359 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.249754 | Sterimol/B1: 4.17202 | Sterimol/B2: 4.35613 | Sterimol/B3: 6.58129 |
Sterimol/B4: 7.49813 | Sterimol/L: 14.1245 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 654.454 | Positive charged surface: 516.778 | Negative charged surface: 137.676 | Volume: 375.625 |
Hydrophobic surface: 590.432 | Hydrophilic surface: 64.022 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |