Physical Properties | | | |
Molecular Weight: 374.423 g/mol | logS: -5.00748 | SlogP: 4.3098 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0212371 | Sterimol/B1: 3.47432 | Sterimol/B2: 3.74309 | Sterimol/B3: 5.12376 |
Sterimol/B4: 9.88228 | Sterimol/L: 18.346 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 662.318 | Positive charged surface: 440.391 | Negative charged surface: 210.856 | Volume: 359.125 |
Hydrophobic surface: 554.003 | Hydrophilic surface: 108.315 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |