Physical Properties | | | |
Molecular Weight: 394.474 g/mol | logS: -4.87989 | SlogP: 2.0618 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0275781 | Sterimol/B1: 2.46821 | Sterimol/B2: 3.17449 | Sterimol/B3: 3.33354 |
Sterimol/B4: 12.2227 | Sterimol/L: 17.9196 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 702.628 | Positive charged surface: 501.635 | Negative charged surface: 189.961 | Volume: 388 |
Hydrophobic surface: 594.506 | Hydrophilic surface: 108.122 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |