Physical Properties | | | |
Molecular Weight: 414.513 g/mol | logS: -3.79654 | SlogP: 3.77887 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.149086 | Sterimol/B1: 3.58441 | Sterimol/B2: 5.05631 | Sterimol/B3: 5.1448 |
Sterimol/B4: 6.90158 | Sterimol/L: 16.7127 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 648.981 | Positive charged surface: 481.258 | Negative charged surface: 162.187 | Volume: 401.5 |
Hydrophobic surface: 570.279 | Hydrophilic surface: 78.702 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |