Physical Properties | | | |
Molecular Weight: 403.506 g/mol | logS: -5.56716 | SlogP: 5.3419 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.242743 | Sterimol/B1: 2.40771 | Sterimol/B2: 4.61226 | Sterimol/B3: 7.38264 |
Sterimol/B4: 8.31578 | Sterimol/L: 15.0021 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 645.686 | Positive charged surface: 384.673 | Negative charged surface: 256.421 | Volume: 383.875 |
Hydrophobic surface: 531.958 | Hydrophilic surface: 113.728 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |