Physical Properties | | | |
Molecular Weight: 417.472 g/mol | logS: -6.56659 | SlogP: 6.1365 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.040579 | Sterimol/B1: 2.27713 | Sterimol/B2: 4.03221 | Sterimol/B3: 5.6093 |
Sterimol/B4: 8.80484 | Sterimol/L: 20.4536 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 701.84 | Positive charged surface: 436.952 | Negative charged surface: 254.832 | Volume: 403.75 |
Hydrophobic surface: 621.253 | Hydrophilic surface: 80.587 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |