Physical Properties | | | |
Molecular Weight: 492.379 g/mol | logS: -5.44488 | SlogP: 1.9641 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0786781 | Sterimol/B1: 2.92017 | Sterimol/B2: 5.64016 | Sterimol/B3: 5.86759 |
Sterimol/B4: 6.81117 | Sterimol/L: 19.871 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 729.055 | Positive charged surface: 442.766 | Negative charged surface: 286.289 | Volume: 442.75 |
Hydrophobic surface: 583.549 | Hydrophilic surface: 145.506 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |