Physical Properties | | | |
Molecular Weight: 394.882 g/mol | logS: -8.0508 | SlogP: 5.80002 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0410496 | Sterimol/B1: 2.08416 | Sterimol/B2: 3.20739 | Sterimol/B3: 4.53716 |
Sterimol/B4: 7.90379 | Sterimol/L: 18.5397 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 632.391 | Positive charged surface: 330.004 | Negative charged surface: 302.387 | Volume: 352.875 |
Hydrophobic surface: 536.943 | Hydrophilic surface: 95.448 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |