Physical Properties | | | |
Molecular Weight: 363.397 g/mol | logS: -5.26859 | SlogP: 3.9485 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0107137 | Sterimol/B1: 2.14469 | Sterimol/B2: 3.21823 | Sterimol/B3: 3.34856 |
Sterimol/B4: 5.97072 | Sterimol/L: 18.8738 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 587.514 | Positive charged surface: 298.055 | Negative charged surface: 284.211 | Volume: 318.875 |
Hydrophobic surface: 340.611 | Hydrophilic surface: 246.903 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |