Physical Properties | | | |
Molecular Weight: 408.498 g/mol | logS: -4.78023 | SlogP: 3.74269 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0393208 | Sterimol/B1: 2.41331 | Sterimol/B2: 3.47572 | Sterimol/B3: 4.10704 |
Sterimol/B4: 7.90301 | Sterimol/L: 21.2615 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 714.784 | Positive charged surface: 441.943 | Negative charged surface: 272.841 | Volume: 406.125 |
Hydrophobic surface: 582.058 | Hydrophilic surface: 132.726 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |