Physical Properties | | | |
Molecular Weight: 483.565 g/mol | logS: -3.91702 | SlogP: 3.28574 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0985614 | Sterimol/B1: 3.81481 | Sterimol/B2: 5.26474 | Sterimol/B3: 6.54694 |
Sterimol/B4: 6.80898 | Sterimol/L: 19.6888 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 768.823 | Positive charged surface: 568.243 | Negative charged surface: 200.581 | Volume: 468.5 |
Hydrophobic surface: 568.013 | Hydrophilic surface: 200.81 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |