Physical Properties | | | |
Molecular Weight: 416.566 g/mol | logS: -3.32384 | SlogP: 1.11107 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0380218 | Sterimol/B1: 2.67308 | Sterimol/B2: 2.93303 | Sterimol/B3: 4.52405 |
Sterimol/B4: 6.26426 | Sterimol/L: 23.0469 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 722.493 | Positive charged surface: 496.635 | Negative charged surface: 225.858 | Volume: 410.25 |
Hydrophobic surface: 553.405 | Hydrophilic surface: 169.088 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |