Physical Properties | | | |
Molecular Weight: 365.389 g/mol | logS: -4.50253 | SlogP: 2.2051 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0627699 | Sterimol/B1: 2.81314 | Sterimol/B2: 2.92374 | Sterimol/B3: 4.96738 |
Sterimol/B4: 10.5206 | Sterimol/L: 15.886 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 622.357 | Positive charged surface: 422.523 | Negative charged surface: 199.833 | Volume: 341.75 |
Hydrophobic surface: 463.327 | Hydrophilic surface: 159.03 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |