Physical Properties | | | |
Molecular Weight: 546.648 g/mol | logS: -6.4585 | SlogP: 4.49282 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.108768 | Sterimol/B1: 2.50644 | Sterimol/B2: 4.83151 | Sterimol/B3: 6.99933 |
Sterimol/B4: 9.33365 | Sterimol/L: 22.0064 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 840.168 | Positive charged surface: 554.884 | Negative charged surface: 275.421 | Volume: 521.75 |
Hydrophobic surface: 650.206 | Hydrophilic surface: 189.962 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |