Physical Properties | | | |
Molecular Weight: 299.255 g/mol | logS: -1.36811 | SlogP: -2.36308 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.146554 | Sterimol/B1: 2.55323 | Sterimol/B2: 3.90296 | Sterimol/B3: 5.04371 |
Sterimol/B4: 6.00402 | Sterimol/L: 12.7182 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 478.907 | Positive charged surface: 265.466 | Negative charged surface: 213.44 | Volume: 249.5 |
Hydrophobic surface: 244.623 | Hydrophilic surface: 234.284 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 6 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |