Physical Properties | | | |
Molecular Weight: 311.722 g/mol | logS: -0.9145 | SlogP: -0.5986 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.168654 | Sterimol/B1: 2.48052 | Sterimol/B2: 4.11763 | Sterimol/B3: 4.24278 |
Sterimol/B4: 7.50984 | Sterimol/L: 14.7121 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 522.445 | Positive charged surface: 327.469 | Negative charged surface: 194.976 | Volume: 258.875 |
Hydrophobic surface: 322.848 | Hydrophilic surface: 199.597 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |