Physical Properties | | | |
Molecular Weight: 462.634 g/mol | logS: -6.78441 | SlogP: 4.7868 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.142666 | Sterimol/B1: 2.62339 | Sterimol/B2: 5.99712 | Sterimol/B3: 6.28487 |
Sterimol/B4: 7.29034 | Sterimol/L: 17.9571 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 733.15 | Positive charged surface: 553.868 | Negative charged surface: 179.281 | Volume: 472.5 |
Hydrophobic surface: 695.439 | Hydrophilic surface: 37.711 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |