Physical Properties | | | |
Molecular Weight: 331.277 g/mol | logS: -1.40757 | SlogP: -0.7538 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.27272 | Sterimol/B1: 3.63726 | Sterimol/B2: 5.05965 | Sterimol/B3: 5.08732 |
Sterimol/B4: 6.63974 | Sterimol/L: 13.9619 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 557.784 | Positive charged surface: 321.816 | Negative charged surface: 235.968 | Volume: 275.375 |
Hydrophobic surface: 324.819 | Hydrophilic surface: 232.965 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |