Physical Properties | | | |
Molecular Weight: 461.606 g/mol | logS: -4.67795 | SlogP: 4.35977 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.284854 | Sterimol/B1: 3.50764 | Sterimol/B2: 3.61048 | Sterimol/B3: 7.63541 |
Sterimol/B4: 7.84738 | Sterimol/L: 15.47 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 690.008 | Positive charged surface: 566.12 | Negative charged surface: 123.326 | Volume: 457.25 |
Hydrophobic surface: 664.852 | Hydrophilic surface: 25.156 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |