Physical Properties | | | |
Molecular Weight: 304.474 g/mol | logS: -5.06183 | SlogP: 4.2051 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.164286 | Sterimol/B1: 2.11634 | Sterimol/B2: 3.10062 | Sterimol/B3: 4.21539 |
Sterimol/B4: 7.25691 | Sterimol/L: 13.7554 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 499.828 | Positive charged surface: 359.159 | Negative charged surface: 140.67 | Volume: 317.125 |
Hydrophobic surface: 374.761 | Hydrophilic surface: 125.067 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 8 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |