Physical Properties | | | |
Molecular Weight: 413.861 g/mol | logS: -6.55629 | SlogP: 4.5268 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0544546 | Sterimol/B1: 2.56088 | Sterimol/B2: 3.51651 | Sterimol/B3: 3.80106 |
Sterimol/B4: 10.9194 | Sterimol/L: 17.6091 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 642.063 | Positive charged surface: 282.147 | Negative charged surface: 359.916 | Volume: 350.75 |
Hydrophobic surface: 483.593 | Hydrophilic surface: 158.47 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 1 | Acid groups: 3 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |